The Radek Maneuver is a scale-up-then-scale-down tactic used in the administration of web services, specifically those deployed under a cloud computing paradigm (by a provider e.g. Amazon Elastic Compute Cloud or Microsoft Azure). == History == Developed by Olivier "Radek" Dabrowski in the mid-2010s, the Radek Maneuver was originally conceived of in using and maintaining applications running on a PaaS system. == Execution == The Radek Maneuver consists of a series of steps, usually executed via the PaaS or web portal interface. The tactic should be used when a service is misbehaving or otherwise experiencing errors, and the suspected cause is the underlying cloud layer, rather than the application layer. This includes networking issues and other "bad box" problems. The steps are as follows: Identify the application or service which is misbehaving. Increase the compute resource (number of CPU cores, amount of ram) for the instance on which the application is running. This is also known as scaling up. Wait for the application to re-deploy and stabilize. Scale back down to the original instance size. == Principle of action == This scale-up-scale-down method is understood to shift the application to a different physical machine underlying the PaaS service or application virtual machine. While this layer of the cloud computing stack is generally out of the access of an application developer (instead in the hands of the cloud provider), the maneuver allows troubleshooting and dodging errors in that layer.
Summify
Summify was a social news aggregator founded by Mircea Paşoi and Cristian Strat, two former Google and Microsoft interns from Romania. The service emailed its users a periodic summary of news articles shared from their social networks based on their relevance and importance. The platform supported Twitter, Facebook, and Google Reader accounts. == History == In 2009, Paşoi and Strat created ReadFu, a plugin that provided a contextual summary and statistics of the target page of a hyperlink. In January 2010, ReadFu was accepted into the Vancouver-based start-up incubator Bootup Labs. On March 20, 2010 the service was renamed to Summify and a private beta began. On August 11, 2010 Paşoi and Strat announced a new direction for the service. It would become a real-time social news reader that aggregates incoming news from social networks and displays articles by importance using social reactions. After some feedback that the users preferred article digests by email more than the real-time news reader version, Summify discontinued the news reader version. In March 2011, Summify completed a Seed round, with investors including Rob Glaser, Accel Partners, and Stewart Butterfield. Summify received coverage from various news and media outlets such as TechCrunch. It was also featured in various news platforms, such as Time, The Globe and Mail, Mashable, VentureBeat, Gizmodo, Lifehacker, and The Next Web. Summify released a free app on the Apple App Store on July 8, 2011. The app allowed users to read their web summaries from iOS mobile devices. Summify was acquired by Twitter on January 19, 2012. The service shut down soon after, on June 22, 2012.
Eimear Kenny
Eimear E. Kenny is a researcher in population genetics and translation genomics, and is the Founding Director of the Institute for Genomic Health, and Endowed Chair and Professor of Genomic Health at the Icahn School of Medicine at Mount Sinai. She is known for novel approaches in computational genomics, advancing the study of human genetic variation and its connection to disease risk and diagnosis. Her research has laid the foundation for integrating artificial intelligence (AI) and genomics into precision medicine and routine clinical care. By combining genomics, computer science, and medicine, her work leverages genomic sequencing technologies and machine learning algorithms to uncover insights that improve patient care, accelerate genomic data analysis, and enable the future of AI-driven healthcare. She has led multiple genomics-based clinical trials, applying computational biology and AI in clinical settings to advance genomic medicine and precision healthcare. == Research == A recipient of the Early-Career Award from the American Society of Human Genetics (USA), Kenny, as of 2024, leads a team in genetics, computer science, and medicine, focusing on genetic ancestry, large-scale genomics, clinical trials, and genomic medicine at the Institute for Genomic Health. The lab works to advance understanding of genetic ancestry and its impact on health in order to inform better clinical medicine models. She is recognized for her work to leverage biobanks for translational genomics and her development of new genetic tests an strategies for health care management. In one study, she and her colleagues investigated genetic disorders that might be under-diagnosed due to insufficient data, and found a variant in a collagen gene associated with Steel syndrome. This syndrome caused short stature and bone and joint issues and was thought to be rare. However, the study revealed it is common in individuals with Puerto Rican ancestry. Three of Kenny's genomic medicine clinical trials assessed how to bring new technology, such as digital apps, or information, such as polygenic risk scores, into routine clinical care. In the 2010s, Kenny was instrumental in several large-scale sequencing studies, including the 1000 Genomes Project, the Exome Sequencing Project, the Genome Sequencing Project, and the Trans-Omics for Precision Medicine. In 2012, she led work that discovered the variant responsible for blond hair in Melanesia, work that was featured in the Smithsonian NHGRI Human Genome Exhibit in Washington, D.C. In 2017, her group was one of the first to demonstrate that polygenic risk scores derived in predominantly European populations have reduced accuracy when applied in populations now widely acknowledged as a major challenge in the field of genomic risk prediction. As of 2024, she is Principal Investigator in many NIH-funded international consortium focused on computational genomics and genomic medicine, including Electronic Medical Records and Genomics, Polygenic Risk Methods in Diverse Populations, and the Human Pangenome Reference Consortium. In 2023, Kenny played a key role in a groundbreaking advancement in genomics research by helping to map a diverse human pangenome—a major shift from reliance on a single reference genome. Unlike the earlier genetic map, based on one man of mixed European and African ancestry in Buffalo, this new pangenome project captures far greater human genetic diversity. As reported by The Washington Post, Kenny's work demonstrates how a more inclusive human genome can drive discoveries in rare genetic diseases, improve genomic medicine, and accelerate the future of precision healthcare. Kenny was co-developer and current license holder for Random Forest adMIXture (RFMix), a patented software for inferring continental and sub-continental ancestry at genomic loci. == Education and career == Kenny graduated from Trinity College Dublin with a BA in Biochemistry in 1999 and did a masters in Bioinformatics at Leeds University. She received her PhD in Computational Genomics at Rockefeller University, and did her post-doctoral work in the lab of Dr. Carlos D. Bustamante at Stanford University. === Academic appointments === As of 2024, at Mount Sinai, she serves as the Endowed Chair and Professor of Genomic Health, Professor at the Department of Medicine and Professor at the Department of Genetics and Genomic Sciences. Since 2018 she has served as the Founding Director of the Institute for Genomic Health, and since 2022, she also serves as the Founding Director of the Center for Translational Genomics. She is also the Director of Translational Research, Division for Genomic Medicine. Former appointments include Assistant Professor at the Department of Genetics and Genomic Sciences and Member at The Charles Bronfman Institute of Personalized Medicine, both at Mount Sinai. She was also Bioinformatics Programmer at the California Institute of Technology, and research assistant at the Massachusetts Institute of Technology. == Publications == As of 2024, Kenny is an advisor to Cell Genomics. Google Scholar reports 50,623 citations, an h-index of 66 and an i10-index of 130. The five most-cited articles she contributed to are: Auton, A; Brooks, LD; Durbin, RM; Garrison, EP; Kang, HM; Korbel, JO; Marchini, JL; McCarthy, S; McVean, GA; Abecasis, GR (2015). "A global reference for human genetic variation". Nature. 526 (7571): 68–74. Bibcode:2015Natur.526...68T. doi:10.1038/nature15393. PMC 4750478. PMID 26432245.. Cited by 14847 Abecasis, GR; Auton, A; Brooks, LD; DePristo, MA; Durbin, RM; Handsaker, RE; Kang, HM; Marth, GT; McVean, GA (2012). "An integrated map of genetic variation from 1,092 human genomes". Nature. 491 (7422): 56–65. Bibcode:2012Natur.491...56T. doi:10.1038/nature11632. PMC 3498066. PMID 23128226.. Cited by 8287 Jacob A. Tennessen et al. Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes.Science337,64–69(2012).DOI:10.1126/science.1219240 Cited by 1886 Taliun, D.; Harris, D.N.; Kessler, M.D.; et al. (2021). "Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program". Nature. 590 (7845): 290–299. Bibcode:2021Natur.590..290T. doi:10.1038/s41586-021-03205-y. PMC 7875770. PMID 33568819.. Cited by 1369 Vilhjálmsson, BJ; et al. (2015). "Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores". Am J Hum Genet. 97 (4): 576–92. doi:10.1016/j.ajhg.2015.09.001. PMC 4596916. PMID 26430803.. Cited by 1327
Norm (artificial intelligence)
Norms can be considered from different perspectives in artificial intelligence to create computers and computer software that are capable of intelligent behaviour. In artificial intelligence and law, legal norms are considered in computational tools to automatically reason upon them. In multi-agent systems (MAS), a branch of artificial intelligence (AI), a norm is a guide for the common conduct of agents, thereby easing their decision-making, coordination and organization. Since most problems concerning regulation of the interaction of autonomous agents are linked to issues traditionally addressed by legal studies, and since law is the most pervasive and developed normative system, efforts to account for norms in artificial intelligence and law and in normative multi-agent systems often overlap. == Artificial intelligence and law == With the arrival of computer applications into the legal domain, and especially artificial intelligence applied to it, logic has been used as the major tool to formalize legal reasoning and has been developed in many directions, ranging from deontic logics to formal systems of argumentation. The knowledge base of legal reasoning systems usually includes legal norms (such as governmental regulations and contracts), and as a consequence, legal rules are the focus of knowledge representation and reasoning approaches to automatize and solve complex legal tasks. Legal norms are typically represented into a logic-based formalism, such as deontic logic. Artificial intelligence and law applications using an explicit representation of norms range from checking the compliance of business processes and the automatic execution of smart contracts to legal expert systems advising people on legal matters. == Multi-agent systems == Norms in multi-agent systems may appear with different degrees of explicitness ranging from fully unambiguous written prescriptions to implicit unwritten norms or tacit emerging patterns. Computer scientists’ studies mirror this polarity. Explicit norms are typically investigated in formal logics (e.g. deontic logics and argumentation) to represent and reason upon them, leading eventually to architecture for cognitive agents, while implicit norms are accounted as patterns emerging from repeated interactions amongst agents (typically reinforced learning agents). Explicit and implicit norms can be used together to coordinate agents. Explicit norms are typically represented as a deontic statement that aims at regulating the life of software agents and the interactions among them. It can be an obligation, a permission or a prohibition, and is often represented with some dialect or extension of Deontic logic. At the opposite, implicit norms are social norms that are not written, and they usually emerge from the repetitive interactions of agents.
Strategic Computing Initiative
The United States government's Strategic Computing Initiative funded research into advanced computer hardware and artificial intelligence from 1983 to 1993. The initiative was designed to support various projects that were required to develop machine intelligence in a prescribed ten-year time frame, from chip design and manufacture, computer architecture to artificial intelligence software. The Department of Defense spent a total of $1 billion on the project. The inspiration for the program was Japan's fifth generation computer project, an enormous initiative that set aside billions for research into computing and artificial intelligence. As with Sputnik in 1957, the American government saw the Japanese project as a challenge to its technological dominance. The British government also funded a program of their own around the same time, known as Alvey, and a consortium of U.S. companies funded another similar project, the Microelectronics and Computer Technology Corporation. The goal of SCI, and other contemporary projects, was nothing less than full machine intelligence. "The machine envisioned by SC", according to Alex Roland and Philip Shiman, "would run ten billion instructions per second to see, hear, speak, and think like a human. The degree of integration required would rival that achieved by the human brain, the most complex instrument known to man." The initiative was conceived as an integrated program, similar to the Apollo moon program, where different subsystems would be created by various companies and academic projects and eventually brought together into a single integrated system. Roland and Shiman wrote that "While most research programs entail tactics or strategy, SC boasted grand strategy, a master plan for an entire campaign." The project was funded by the Defense Advanced Research Projects Agency and directed by the Information Processing Technology Office (IPTO). By 1985 it had spent $100 million, and 92 projects were underway at 60 institutions: half in industry, half in universities and government labs. Robert Kahn, who directed IPTO in those years, provided the project with its early leadership and inspiration. Clint Kelly managed the SC Initiative for three years and developed many of the specific application programs for DARPA, such as the Autonomous Land Vehicle. By the late 1980s, it was clear that the project would fall short of realizing the hoped-for levels of machine intelligence. Program insiders pointed to issues with integration, organization, and communication. When Jack Schwarz ascended to the leadership of IPTO in 1987, he cut funding to artificial intelligence research (the software component) "deeply and brutally", "eviscerating" the program (wrote Pamela McCorduck). Schwarz felt that DARPA should focus its funding only on those technologies which showed the most promise. In his words, DARPA should "surf", rather than "dog paddle", and he felt strongly AI was not "the next wave". The project was superseded in the 1990s by the Accelerated Strategic Computing Initiative and then by the Advanced Simulation and Computing Program. These later programs did not include artificial general intelligence as a goal, but instead focused on supercomputing for large scale simulation, such as atomic bomb simulations. The Strategic Computing Initiative of the 1980s is distinct from the 2015 National Strategic Computing Initiative—the two are unrelated. == Results == Although the program failed to meet its goal of high-level machine intelligence, it did meet some of its specific technical objectives, for example those of autonomous land navigation. The Autonomous Land Vehicle program and its sister Navlab project at Carnegie Mellon University, in particular, laid the scientific and technical foundation for many of the driverless vehicle programs that came after it, such as the Demo II and III programs (ALV being Demo I), Perceptor, and the DARPA Grand Challenge. The use of video cameras plus laser scanners and inertial navigation units pioneered by the SCI ALV program form the basis of almost all commercial driverless car developments today. It also helped to advance the state of the art of computer hardware to a considerable degree. On the software side, the initiative funded development of the Dynamic Analysis and Replanning Tool (DART), a program that handled logistics using artificial intelligence techniques. This was a huge success, saving the Department of Defense billions during Desert Storm. Introduced in 1991, DART had by 1995 offset the monetary equivalent of all funds DARPA had channeled into AI research for the previous 30 years combined.
Human visual system model
A human visual system model (HVS model) is used by image processing, video processing and computer vision experts to deal with biological and psychological processes that are not yet fully understood. Such a model is used to simplify the behaviors of what is a very complex system. As our knowledge of the true visual system improves, the model is updated. Psychovisual study is the study of the psychology of vision. The human visual system model can produce desired effects in perception and vision. Examples of using an HVS model include color television, lossy compression, and Cathode-ray tube (CRT) television. Originally, it was thought that color television required too high a bandwidth for the then available technology. Then it was noticed that the color resolution of the HVS was much lower than the brightness resolution; this allowed color to be squeezed into the signal by chroma subsampling. Another example is lossy image compression, like JPEG. Our HVS model says we cannot see high frequency detail, so in JPEG we can quantize these components without a perceptible loss of quality. Similar concepts are applied in audio compression, where sound frequencies inaudible to humans are band-stop filtered. Several HVS features are derived from evolution when we needed to defend ourselves or hunt for food. We often see demonstrations of HVS features when we are looking at optical illusions. == Block diagram of HVS == == Assumptions about the HVS == Low-pass filter characteristic (limited number of rods in human eye): see Mach bands Lack of color resolution (fewer cones in human eye than rods) Motion sensitivity More sensitive in peripheral vision Stronger than texture sensitivity, e.g. viewing a camouflaged animal Texture stronger than disparity – 3D depth resolution does not need to be so accurate Integral Face recognition (babies smile at faces) Depth inverted face looks normal (facial features overrule depth information) Upside down face with inverted mouth and eyes looks normal == Examples of taking advantage of an HVS model == Flicker frequency of film and television using persistence of vision to fool viewer into seeing a continuous image Interlaced television painting half images to give the impression of a higher flicker frequency Color television (chrominance at half resolution of luminance corresponding to proportions of rods and cones in eye) Image compression (difficult to see higher frequencies more harshly quantized) Motion estimation (use luminance and ignore color) Watermarking and Steganography
Logic Theorist
Logic Theorist is a computer program completed in 1956 by Allen Newell, Herbert A. Simon, and Cliff Shaw. It was the first program deliberately engineered to perform automated reasoning, and has been described as "the first artificial intelligence program". Logic Theorist proved 38 of the first 52 theorems in chapter two of Whitehead and Bertrand Russell's Principia Mathematica, and found new and shorter proofs for some of them. == History == In 1955, when Newell and Simon began to work on the Logic Theorist, the field of artificial intelligence did not yet exist; the term "artificial intelligence" would not be coined until the following summer. Simon was a political scientist who had previously studied the way bureaucracies function as well as developing his theory of bounded rationality (for which he would later win the Nobel Memorial Prize in Economic Sciences in 1978). He believed the study of business organizations requires, like artificial intelligence, an insight into the nature of human problem solving and decision making. Simon has stated that when consulting at RAND Corporation in the early 1950s, he saw a printer typing out a map, using ordinary letters and punctuation as symbols. This led him to think that a machine that could manipulate symbols could simulate decision making and possibly even the process of human thought. The program that printed the map had been written by Newell, a RAND scientist studying logistics and organization theory. For Newell, the decisive moment was in 1954 when Oliver Selfridge came to RAND to describe his work on pattern matching. Watching the presentation, Newell suddenly understood how the interaction of simple, programmable units could accomplish complex behavior, including the intelligent behavior of human beings. "It all happened in one afternoon," he would later say. It was a rare moment of scientific epiphany. "I had such a sense of clarity that this was a new path, and one I was going to go down. I haven't had that sensation very many times. I'm pretty skeptical, and so I don't normally go off on a toot, but I did on that one. Completely absorbed in it—without existing with the two or three levels consciousness so that you're working, and aware that you're working, and aware of the consequences and implications, the normal mode of thought. No. Completely absorbed for ten to twelve hours." Newell and Simon began to talk about the possibility of teaching machines to think. Their first project was a program that could prove mathematical theorems like the ones used in Bertrand Russell and Alfred North Whitehead's Principia Mathematica. They enlisted the help of computer programmer Cliff Shaw, also from RAND, to develop the program. (Newell says "Cliff was the genuine computer scientist of the three".) The first version was hand-simulated: they wrote the program onto 3x5 cards and, as Simon recalled:In January 1956, we assembled my wife and three children together with some graduate students. To each member of the group, we gave one of the cards, so that each one became, in effect, a component of the computer program ... Here was nature imitating art imitating nature. They succeeded in showing that the program could successfully prove theorems as well as a talented mathematician. Eventually Shaw was able to run the program on the computer at RAND's Santa Monica facility. In the summer of 1956, John McCarthy, Marvin Minsky, Claude Shannon and Nathan Rochester organized a conference on the subject of what they called "artificial intelligence" (a term coined by McCarthy for the occasion). Newell and Simon proudly presented the group with the Logic Theorist. It was met with a lukewarm reception. Pamela McCorduck writes "the evidence is that nobody save Newell and Simon themselves sensed the long-range significance of what they were doing." Simon confides that "we were probably fairly arrogant about it all" and adds: They didn't want to hear from us, and we sure didn't want to hear from them: we had something to show them! ... In a way it was ironic because we already had done the first example of what they were after; and second, they didn't pay much attention to it. Logic Theorist soon proved 38 of the first 52 theorems in chapter 2 of the Principia Mathematica. The proof of theorem 2.85 was actually more elegant than the proof produced laboriously by hand by Russell and Whitehead (2026-03-20: What is called here Theorem 2.85 is, in fact, numbered as 2.53 in the page 107 of the 1963 Cambridge University Press edition (https://www.uhu.es/francisco.moreno/gii_mac/docs/Principia_Mathematica_vol1.pdf) and which appears, under the same 2.53 number, on page 112 of the 1910 CUP Edition, according to the digitalization on wikibooks (https://en.wikisource.org/wiki/Russell_%26_Whitehead%27s_Principia_Mathematica/Part_1/Section_A#Discussion_2)). Simon was able to show the new proof to Russell himself who "responded with delight". They attempted to publish the new proof in The Journal of Symbolic Logic, but it was rejected on the grounds that a new proof of an elementary mathematical theorem was not notable, apparently overlooking the fact that one of the authors was a computer program. Newell and Simon formed a lasting partnership, founding one of the first AI laboratories at the Carnegie Institute of Technology and developing a series of influential artificial intelligence programs and ideas, including the General Problem Solver, Soar, and their unified theory of cognition. == Architecture == The Logic Theorist is a program that performs logical processes on logical expressions. The Logic Theorist operates on the following principles: === Expressions === An expression is made of elements. There are two kinds of memories: working and storage. Each working memory contains a single element. The Logic Theorist usually uses 1 to 3 working memories. Each storage memory is a list representing a full expression or a set of elements. In particular, it contains all the axioms and proven logical theorems. An expression is an abstract syntax tree, each node being an element with up to 11 attributes. For example, the logical expression ¬ P → ( Q ∧ ¬ P ) {\displaystyle \neg P\to (Q\wedge \neg P)} is represented as a tree with a root element representing → {\displaystyle \to } . Among the attributes of the root element are pointers to the two elements representing the subexpressions ¬ P {\displaystyle \neg P} and Q ∧ ¬ P {\displaystyle Q\wedge \neg P} . === Processes === There are four kinds of processes, from the lowest to the highest level. Instruction: These are similar to assembly code. They may either perform a primitive operation on an expression in working memory, or perform a conditional jump to another instruction. An example is "put the right sub-element of working-memory 1 to working-memory 2" Elementary process: These are similar to subroutines. A sequence of instructions that can be called. Method: A sequence of elementary processes. There are 4 methods: substitution: given an expression, it attempts to transform it to a proven theorem or axiom by substitutions of variables and logical connectives. detachment: given expression B {\displaystyle B} , it attempts to find a proven theorem or axiom of form A → B ′ {\displaystyle A\to B'} , where B ′ {\displaystyle B'} yields B {\displaystyle B} after substitution, then attempts to prove A {\displaystyle A} by substitution. chaining forward: given expression A → C {\displaystyle A\to C} , it attempts to find for a proven theorem or axiom of form A → B {\displaystyle A\to B} , then attempt to prove B → C {\displaystyle B\to C} by substitution. chaining backward: given expression A → C {\displaystyle A\to C} , it attempts to find for a proven theorem or axiom of form B → C {\displaystyle B\to C} , then attempt to prove A → B {\displaystyle A\to B} by substitution. executive control method: This method applies each of the 4 methods in sequence to each theorem to be proved. == Logic Theorist's influence on AI == Logic Theorist introduced several concepts that would be central to AI research: Reasoning as search Logic Theorist explored a search tree: the root was the initial hypothesis, each branch was a deduction based on the rules of logic. Somewhere in the tree was the goal: the proposition the program intended to prove. The pathway along the branches that led to the goal was a proof – a series of statements, each deduced using the rules of logic, that led from the hypothesis to the proposition to be proved. Heuristics Newell and Simon realized that the search tree would grow exponentially and that they needed to "trim" some branches, using "rules of thumb" to determine which pathways were unlikely to lead to a solution. They called these ad hoc rules "heuristics", using a term introduced by George Pólya in his classic book on mathematical proof, How to Solve It. (Newell had taken courses from Pólya at Stanford). Heuristics would become an important area o